Gingival Fibroblasts image

Identifying a New Treatment for Periodontitis

Human Fibroblasts: Important Cells in Wound Healing and Inflammation Fibroblasts are the most common cell type comprising the connective tissue in humans and other mammals. These spindle-shaped cells synthesize extracellular matrix proteins that provide the structural framework, or stroma, for animal tissues. Besides their well-known structural role, fibroblasts are important in the wound healing response…
Human Fibroblast Cells

Mitochondrial Function Studied Using Decompression Sickness Conditions

Fibroblast Function in Connective Tissue Fibroblasts are the most common cell type found in connective tissue throughout the body. Their main role is to produce the extracellular matrix and collagen fibers that support the connective tissue structure. In addition to their role in maintaining connective tissue, fibroblasts are also key players in wound healing. Following…
DNA Cells

A Half-Year Review of the Latest Research with Lifeline® Multifunctional Cells

Halfway through 2017, here’s a recap of how researchers are using Lifeline® cells to study different disease mechanisms and biological processes. Lifeline® cells are being used to: engineer in vitro airway models, represent normal tissue controls for cancer studies, model capillary formation, and more. (We carry cells from 15 different tissue types and below are…
Woman with sunscreen on

Making Strides in Skin Cell Research Utilizing Lifeline® Keratinocytes and Melanocytes

Cells of the Skin: Keratinocytes and Melanocytes The skin has three layers, the epidermis (outermost), the dermis (middle), and the hypodermis (the innermost). The epidermis is largely composed of keratinocytes, which form a barrier against the external environment and play a role in wound repair. Melanocytes are another common cell type found in the skin.…
Lifeline Normal Human Cells are Better Controls

Lifeline® Cells: Better Normal Controls for Therapeutic Development

Identifying the best cells to use as controls is critical. In particular, finding a “normal”, non-cancer control cell to test anti-cancer therapies is a challenge our customers often face. Lifeline® has the tools to help – read on to learn more. The phrase “normal cells” can sometimes be misleading. In fact, “normal” immortalized cell lines…
Dermal Fibroblasts and Cancer

Research Applications of Lifeline Cells and Culture Media

Many research groups have demonstrated the diversity of our many cell types. A few of the many research applications are highlighted here: Lifeline® Dermal Fibroblasts as normal, non-transformed control cells Prostate and pancreatic cancer are two of the most deadly human cancers with limited treatment options. Therefore, there is much interest in developing new targeted…
FibroLife S2 Fibroblasts Medium Complete Kit LL-0011

FibroLife S2 Fibroblast Medium Complete Kit

Optimized for Culturing Primary Human Fibroblasts and Pre-Adipocyte Mesenchymal Stem Cells in a Low-Serum Environment.  FibroLife S2 supports the growth of these cells in a 2% serum environment at rates equal to or greater than comparable media supplemented with 2% to 10% FBS. Primary Cells cultured in FibroLife medium out-perform cells grown in any similar medium…
FibroLife Fibroblast Medium Complete Kit LL-0001

FibroLife Fibroblast Serum Free Medium Complete Kit

FibroLife Serum-Free is a defined medium optimized specifically for the serum-free culture of Primary Human Fibroblasts.  FibroLife Serum-Free supports the growth of these Primary Cells in a serum-free environment at rates equal to or greater than media supplemented with 2% to 10% FBS. Primary Fibroblasts cultured in Lifeline® medium out-perform cells grown in any similar medium. …
Man smoking outside

Strategies for Cardiovascular Risk Reduction in Smokers

For American Heart Month, we want to highlight the importance of advancing cardiovascular research to better understand vascular health, heart function, disease mechanisms, and to develop new therapies for disease treatment. Cardiovascular disease (CVD) remains the leading cause of death in the United States, claiming the lives of approximately 695,000 Americans in 2021 alone. Cigarette…