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HUVECs as In Vitro Models of Endothelial Barrier Function
Human umbilical vein endothelial cells (HUVECs) are a widely used source of primary endothelial cells. First isolated in the 1970s, HUVECs are a popular tool for researchers due to their availability and ease of culture for in vitro studies of the vasculature and angiogenesis. The endothelium is the thin layer of endothelial cells that lines…
Quality Data Relies on Quality Reagents
The ability to culture cells in vitro has provided scientists with insight into many tissue and organ systems in the human body. In order to obtain high quality, reliable results, it is imperative that experiments are conducted using high-quality cell culture reagents. Of critical importance is the quality of cell culture media to ensure the…
Effects of Inorganic Arsenic on Prostate Cancer Development
Prostate cancer is one of the leading indications affecting men today, with an estimated 1 in 9 men diagnosed in their lifetime. Significant effort is being put behind understanding the biology of the male prostate and studying the mechanisms that drive tumorigenesis in hopes of finding ways to mitigate cancer progression or to identify potential…
Helping to Identify New Therapeutic Targets for Covid-19
Lifeline Aortic Smooth Muscle Cells in Covid-19 Research The emergence of SARS-CoV-2 or COVID-19 has dramatically changed the world we live in today. Considerable resources in the medical and scientific communities are being put into understanding its mechanism of action, which can provide insight into new treatments, diagnostic tests, and vaccine options. It is exciting…
Thawing and Seeding Lifeline Primary Cells