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Drug Repurposing to Treat COVID-19 Induced Lung Injury
The rapid spread of COVID-19 during the global pandemic has led many scientists and researchers to look towards repurposing existing FDA-approved drugs, outside the scope of their originally designated purposes, to expedite the delivery of effective treatments on the shortened time-scale required to treat COVID-19 patients owing to their proven safe for human use in…
Obesity-Driven Increase in Endometrial Cancer Risk
Endometrial cancer (EC), sometimes called uterine cancer, begins in the layer of cells that form the lining (endometrium) of the uterus and is the most common cancer of the female reproductive organs. ECs are commonly divided into estrogen-dependent Type I and the more clinically aggressive estrogen-independent Type II, where Type I tumors comprise the large…
The Role of SO2 in Pulmonary Vascular Remodeling
Chronic obstructive pulmonary disease (COPD) is the third most common cause of death in the United States. The incidence of aging and age-related cardiopulmonary diseases like COPD has become more prevalent over the years as the average life expectancy has increased in the population. COPD is characterized by chronic inflammation that restricts airflow in the…
Circadian Clock Protein BMAL1 Protect Against UVB Damage
The skin is the largest organ of the human body composed of the epidermis (upper or outer layer) and the dermis (lower or inner layer). The epidermis, which is made up of three kinds of cells: keratinocytes, basal cells, and melanocytes, is susceptible to DNA damage caused by exposure to harmful solar ultraviolet radiation (UVR).…
Thawing and Seeding Lifeline Primary Cells