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Endothelial Cells: The Regulators of Blood Vessels

Endothelial Cells

Endothelial Cells and Culture Methods Endothelial cells line the blood and lymphatic vessels of the body, providing important regulation of vessel integrity, blood pressure, wound healing, and formation of new vessels. In particular, many endothelial cell functions are…

Multipotent and Differentiate Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal Stem Cells: Adult Stem Cells with Multiple Destinies Although totipotent stem cells exist only during early embryogenesis, many adult tissues retain adult stem cells, which are multipotent and can differentiate into multiple differentiated cell types. One of…

Using Lifeline® Lung-Airway Cells to Study Viral Infection

Lung/Airway Cells

The Lung-Airway Epithelium When air enters the respiratory system, it travels through the trachea and into one of the two bronchi, which lead to either lung as they branch into bronchioles. Finally, in the lung, the bronchioles terminate…

Introducing NEW Skeletal Muscle Satellite Cells

Skeletal Muscle Cells

NEW Skeletal Muscle Satellite Cells Skeletal muscle controls the voluntary movement of the skeletal system. Striated myofibers are the functional contractile unit of skeletal muscle and are composed of individual myocytes that fuse to form each multinucleated myofiber.…

Studies Investigate Role of Smooth Muscle Cells in Vascular Function and Disease

Smooth Muscle Cells

Vascular Smooth Muscle Cells Regulate Vessel Homeostasis and Dysfunction Vascular smooth muscle cells (VSMCs) are found in blood vessel walls and regulate various aspects of vessel homeostasis, including contraction, dilation, and vessel remodeling. VSMCs can exist as one…

Lifeline® Prostate Epithelial Cells Used to Help Isolate Prostate Cancer Stem Cells

Prostate Epithelial Cells

The Prostate: Anatomy and Epithelial Organization The prostate is part of the male reproductive system that secretes part of the fluid that makes up semen. The urethra runs through the prostate from the bladder, and semen progresses from…

Studies of the Complexities of the Human Female Reproductive System

Female Reproductive Cells

The Human Female Reproductive System and Associated Cancers The female reproductive system is complex. Female gametes, eggs or ova, develop and mature in the two ovaries. Once every month, an egg exits either ovary into the fallopian tube,…

The Role of the Mammary Gland in Breast Cancer

Mammary Epithelial Cells

The mammary gland is composed of a glandular ductal network. These ducts are lined by a protective layer of epithelial cells, and also contain myoepithelial cells that aid in contraction. The terminal duct-lobular unit, which makes up the…

A Half-Year Review of the Latest Research with Lifeline® Multifunctional Cells

Lifeline Cells and Media

Halfway through 2017, here’s a recap of how researchers are using Lifeline® cells to study different disease mechanisms and biological processes. Lifeline® cells are being used to: engineer in vitro airway models, represent normal tissue controls for cancer…

Endothelial Cells: Regulators of Blood Vessel Homeostasis

Endothelial Cells

Endothelial cells line the blood vessels of the body and participate in significant crosstalk with the blood and tissues to maintain blood pressure and vessel homeostasis through regulation of vasodilation and vasoconstriction. In particular, endothelial cells have been…

Making Strides in Skin Cell Research Utilizing Lifeline® Keratinocytes and Melanocytes

Melanocytes and Keratinocytes

Cells of the Skin: Keratinocytes and Melanocytes The skin has three layers, the epidermis (outermost), the dermis (middle), and the hypodermis (the innermost). The epidermis is largely composed of keratinocytes, which form a barrier against the external environment…

Lifeline® Dermal Fibroblasts Utilized in Wound Healing Study

Fibroblasts

Fibroblasts: Important Players in Wound Healing Fibroblasts are a mesenchymal cell type, known for their spindle shape. Although they are present in most tissue types, they are often found in connective tissue due their function in producing extracellular…

Latest Research on The Excretory System: Cleaning up the Waste

Renal Epithelial Cells

The excretory system starts at the kidneys, a pair of organs that detoxify and remove waste from the blood. This waste, in the form of urine, is transported through the ureters to the bladder, where urine is stored…

Corneal Epithelial Cells in Ocular Hypertension Study

Corneal Epithelial Cells

The Eye: Window to the Brain The eyes are composed of many parts that together, sense and interpret light, enabling the formation of images via the brain. The front of the eye is called the cornea, and it…

Lifeline® Cells: Better Normal Controls for Therapeutic Development

Lifeline Cells and Media

Identifying the best cells to use as controls is critical. In particular, finding a “normal”, non-cancer control cell to test anti-cancer therapies is a challenge our customers often face. Lifeline® has the tools to help – read on…

Vascular Smooth Muscle Cells: Regulators of Blood Vessel Function

Smooth Muscle Cells

Smooth muscle cells (SMCs) are present in most contractile organs, including the bladder, gastrointestinal tract, and blood vessels. Smooth muscle cells in blood vessels are termed vascular smooth muscle cells (VSMCs), and are responsible for maintaining blood pressure…

Introducing Lifeline® Cardiac Microvascular Endothelial Cells and Cardiac Fibroblasts

Cardiac Cells

For over 10 years, Lifeline Cell Technology has produced some of the world’s best normal human endothelial cells and normal human fibroblast cells. Additionally, we have developed low serum, serum-free, or xeno-free media, individually optimized for culturing each…

Endothelial Cells as Blood Vessel Barriers — The Latest Research Studies

Endothelial Cells

Endothelial cells form a monolayer that lines the lumen of blood vessels, provides an essential protective barrier, and regulates vessel and blood pressure homeostasis. Endothelial cells are also involved in forming new blood vessels, a process called angiogenesis.…

Male and Female Reproductive Systems Latest Research Studies

Female Reproductive Cells, Male Reproductive Cells

The male gonads are the testes, which are housed in the scrotum. The testes produce sperm (male gametes) and testosterone (the main male hormone). Following production in the testes, sperm move through the epididymis and into the vas…

Keratinocytes: Barrier to the Outside World

Keratinocytes

The epidermis is the outermost layer of the skin, which covers the entire body and provides an essential barrier against the external environment. The most common epidermal cell type is the keratinocyte. Keratinocytes are born in the basal…