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Keratinocytes and Dermal Fibroblasts: External Layers for Internal Protection

Melanocytes and Keratinocytes

The Multiple Layers and Cell Types of the Skin The skin is the ultimate barrier to the external environment, with a coverage area of the entire body. To perform its specialized functions, the skin is composed of multiple…

Endothelial Cells: Research in Cardiovascular Disease and Mesothelioma

Endothelial Cells

Endothelial Cells: Regulators of Vessel Homeostasis and Angiogenesis Endothelial cells line the blood vessels of the circulatory system and play major roles in cardiovascular homeostasis. Through extensive crosstalk with the circulating blood and various cell types contained in…

Determining the Role of JNK in Anoikis Using Mammary Epithelial Cells

Mammary Epithelial Cells

Mammary Gland Development The mammary gland is derived from the ectoderm, the outer layer of the embryo, and is formed into a series of ducts from which milk is produced. Although present at birth, the mammary gland undergoes…

Bladder Epithelial Cells: The Role of SETD6 on Bladder Cancer Growth and Survival

Bladder Epithelial Cells, Renal Epithelial Cells

The Excretory System: Waste Removal Experts Waste is removed from the body through an elegant filtration system that begins in the kidneys. The renal artery delivers blood to the kidneys, and in a series of filtration steps through…

Lifeline Cell Technology Adds Fallopian Tube Epithelial Cells to Catalog

Female Reproductive Cells

Now Available from Lifeline®: Fallopian Tube Epithelial Cells! The human female reproductive system is responsible for the development of eggs (the female gametes) the production of hormones (progesterone and estrogen), and importantly, supports development and delivery of a…

Airway Epithelium: Advances in Cell Culture Techniques Help Mimic this Complex Environment

Lung/Airway Cells

The Airway Epithelium and Air-Liquid Interface Culture A single later of epithelial cells lines many of our internal organs, including the airway. The airway epithelium is composed of multiple differentiated cell types that form a barrier against pathogens…

Smooth Muscle and Endothelial Cells: Their Critical Role in Blood Flow and Vascular Homeostasis

Smooth Muscle Cells

Large Vessel Endothelial and Smooth Muscle Cells The vessels that make up the circulatory system are multi-layered complex organs. Arteries carry oxygenated blood away from the heart to the tissues of the body and veins carry de-oxygenated blood…

Fibroblasts Studies: The Mitochondria and the Cytoskeleton, and Treating Yeast Biofilms

Fibroblasts

Fibroblasts are the main cell type in stromal tissue, the supporting tissue of an organ that contains structural and connective components. They are a multifunctional cell type whose main function is to secrete extracellular matrix, which forms the…

Microvascular Endothelial Cells and the Latest Circulatory System Research

Endothelial Cells

Endothelial Cells and the Circulatory System Vascular endothelial cells are multi-functional cells that line the vessels of the circulatory system. Endothelial cell monolayers form the innermost layer of vessels, serving protective and barrier functions, and interacting with factors…

Human Cells Research Studies Using Lifeline Cells: 2017 Review

Lifeline Cells and Media

Lifeline® Cells in 2017 It’s the end of the year again and here on the Lifeline® Cell Technology blog you have been keeping up with the various ways researchers from many fields have used Lifeline® cells. We are…

Keratinocytes and Melanocytes Skin Barrier Function Studies

Keratinocytes, Melanocytes and Keratinocytes

The Barrier Function of the Skin Protects the Body from the External Environment The skin is the largest organ of the body and as the outer covering of the body, has a significant protective role. The outermost layer…

Lifeline® Introduces New Cervical Epithelial Cells to Female Reproductive Catalog

Female Reproductive Cells

Cervical Cancer: Facts, Statistics, and Prevention The cervix is part of the female reproductive system and lies at the base of the uterus. The American Cancer Society estimates that in 2017, 12,820 women will be diagnosed with cervical…

Endothelial Cells: The Regulators of Blood Vessels

Endothelial Cells

Endothelial Cells and Culture Methods Endothelial cells line the blood and lymphatic vessels of the body, providing important regulation of vessel integrity, blood pressure, wound healing, and formation of new vessels. In particular, many endothelial cell functions are…

Multipotent and Differentiate Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal Stem Cells: Adult Stem Cells with Multiple Destinies Although totipotent stem cells exist only during early embryogenesis, many adult tissues retain adult stem cells, which are multipotent and can differentiate into multiple differentiated cell types. One of…

Using Lifeline® Lung-Airway Cells to Study Viral Infection

Lung/Airway Cells

The Lung-Airway Epithelium When air enters the respiratory system, it travels through the trachea and into one of the two bronchi, which lead to either lung as they branch into bronchioles. Finally, in the lung, the bronchioles terminate…

Introducing NEW Skeletal Muscle Satellite Cells

Skeletal Muscle Cells

NEW Skeletal Muscle Satellite Cells Skeletal muscle controls the voluntary movement of the skeletal system. Striated myofibers are the functional contractile unit of skeletal muscle and are composed of individual myocytes that fuse to form each multinucleated myofiber.…

Studies Investigate Role of Smooth Muscle Cells in Vascular Function and Disease

Smooth Muscle Cells

Vascular Smooth Muscle Cells Regulate Vessel Homeostasis and Dysfunction Vascular smooth muscle cells (VSMCs) are found in blood vessel walls and regulate various aspects of vessel homeostasis, including contraction, dilation, and vessel remodeling. VSMCs can exist as one…

Lifeline® Prostate Epithelial Cells Used to Help Isolate Prostate Cancer Stem Cells

Prostate Epithelial Cells

The Prostate: Anatomy and Epithelial Organization The prostate is part of the male reproductive system that secretes part of the fluid that makes up semen. The urethra runs through the prostate from the bladder, and semen progresses from…

Studies of the Complexities of the Human Female Reproductive System

Female Reproductive Cells

The Human Female Reproductive System and Associated Cancers The female reproductive system is complex. Female gametes, eggs or ova, develop and mature in the two ovaries. Once every month, an egg exits either ovary into the fallopian tube,…

The Role of the Mammary Gland in Breast Cancer

Mammary Epithelial Cells

The mammary gland is composed of a glandular ductal network. These ducts are lined by a protective layer of epithelial cells, and also contain myoepithelial cells that aid in contraction. The terminal duct-lobular unit, which makes up the…