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Studies Investigate Role of Smooth Muscle Cells in Vascular Function and Disease

Smooth Muscle Cells

Vascular Smooth Muscle Cells Regulate Vessel Homeostasis and Dysfunction Vascular smooth muscle cells (VSMCs) are found in blood vessel walls and regulate various aspects of vessel homeostasis, including contraction, dilation, and vessel remodeling. VSMCs can exist as one…

Lifeline® Prostate Epithelial Cells Used to Help Isolate Prostate Cancer Stem Cells

Prostate Epithelial Cells

The Prostate: Anatomy and Epithelial Organization The prostate is part of the male reproductive system that secretes part of the fluid that makes up semen. The urethra runs through the prostate from the bladder, and semen progresses from…

Studies of the Complexities of the Human Female Reproductive System

Female Reproductive Cells

The Human Female Reproductive System and Associated Cancers The female reproductive system is complex. Female gametes, eggs or ova, develop and mature in the two ovaries. Once every month, an egg exits either ovary into the fallopian tube,…

The Role of the Mammary Gland in Breast Cancer

Mammary Epithelial Cells

The mammary gland is composed of a glandular ductal network. These ducts are lined by a protective layer of epithelial cells, and also contain myoepithelial cells that aid in contraction. The terminal duct-lobular unit, which makes up the…

A Half-Year Review of the Latest Research with Lifeline® Multifunctional Cells

Lifeline Cells and Media

Halfway through 2017, here’s a recap of how researchers are using Lifeline® cells to study different disease mechanisms and biological processes. Lifeline® cells are being used to: engineer in vitro airway models, represent normal tissue controls for cancer…

Endothelial Cells: Regulators of Blood Vessel Homeostasis

Endothelial Cells

Endothelial cells line the blood vessels of the body and participate in significant crosstalk with the blood and tissues to maintain blood pressure and vessel homeostasis through regulation of vasodilation and vasoconstriction. In particular, endothelial cells have been…

Making Strides in Skin Cell Research Utilizing Lifeline® Keratinocytes and Melanocytes

Melanocytes and Keratinocytes

Cells of the Skin: Keratinocytes and Melanocytes The skin has three layers, the epidermis (outermost), the dermis (middle), and the hypodermis (the innermost). The epidermis is largely composed of keratinocytes, which form a barrier against the external environment…

Lifeline® Dermal Fibroblasts Utilized in Wound Healing Study

Fibroblasts

Fibroblasts: Important Players in Wound Healing Fibroblasts are a mesenchymal cell type, known for their spindle shape. Although they are present in most tissue types, they are often found in connective tissue due their function in producing extracellular…

Latest Research on The Excretory System: Cleaning up the Waste

Renal Epithelial Cells

The excretory system starts at the kidneys, a pair of organs that detoxify and remove waste from the blood. This waste, in the form of urine, is transported through the ureters to the bladder, where urine is stored…

Corneal Epithelial Cells in Ocular Hypertension Study

Corneal Epithelial Cells

The Eye: Window to the Brain The eyes are composed of many parts that together, sense and interpret light, enabling the formation of images via the brain. The front of the eye is called the cornea, and it…

Lifeline® Cells: Better Normal Controls for Therapeutic Development

Lifeline Cells and Media

Identifying the best cells to use as controls is critical. In particular, finding a “normal”, non-cancer control cell to test anti-cancer therapies is a challenge our customers often face. Lifeline® has the tools to help – read on…

Vascular Smooth Muscle Cells: Regulators of Blood Vessel Function

Smooth Muscle Cells

Smooth muscle cells (SMCs) are present in most contractile organs, including the bladder, gastrointestinal tract, and blood vessels. Smooth muscle cells in blood vessels are termed vascular smooth muscle cells (VSMCs), and are responsible for maintaining blood pressure…

Introducing Lifeline® Cardiac Microvascular Endothelial Cells and Cardiac Fibroblasts

Cardiac Cells

For over 10 years, Lifeline Cell Technology has produced some of the world’s best normal human endothelial cells and normal human fibroblast cells. Additionally, we have developed low serum, serum-free, or xeno-free media, individually optimized for culturing each…

Endothelial Cells as Blood Vessel Barriers — The Latest Research Studies

Endothelial Cells

Endothelial cells form a monolayer that lines the lumen of blood vessels, provides an essential protective barrier, and regulates vessel and blood pressure homeostasis. Endothelial cells are also involved in forming new blood vessels, a process called angiogenesis.…

Male and Female Reproductive Systems Latest Research Studies

Female Reproductive Cells, Male Reproductive Cells

The male gonads are the testes, which are housed in the scrotum. The testes produce sperm (male gametes) and testosterone (the main male hormone). Following production in the testes, sperm move through the epididymis and into the vas…

Keratinocytes: Barrier to the Outside World

Keratinocytes

The epidermis is the outermost layer of the skin, which covers the entire body and provides an essential barrier against the external environment. The most common epidermal cell type is the keratinocyte. Keratinocytes are born in the basal…

The Airway Epithelium: Guardian Against Respiratory Infection

Lung/Airway Cells

Like many organs, the airway is lined by a single layer of epithelial cells that form the barrier between the external and internal environments. The epithelium is the first line of defense against inhaled pathogens, particularly respiratory viruses…

Fibroblasts: Roles in Homeostasis, Wound Healing, and Cancer

Fibroblasts

Fibroblasts are one of the most common types of stromal cells in the body and are responsible for generating extracellular matrix (ECM) components that support the tissue in which they exist. There is tremendous crosstalk between fibroblasts in…

Review of Research Studies using Lifeline® Cells in 2016

Lifeline Cells and Media

It is the end of the year, so we thought we would take a look back to see how our cells have been used over the past year. Lifeline® provides cells from many organ sites that can be…

Culture Media: the Backbone of Your Cell Culture Experiments

Cell Culture Medium

The quality of cell culture media is critical for maintaining integrity of cells in culture and consistency between experiments. At Lifeline®, we have highly stringent quality control processes to ensure your experiments can be efficiently reproduced. We offer…