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Keratinocytes in Research: Epidermal Differentiation and Senescence

Keratinocytes, Lifeline Cells and Media

Function and Differentiation of Keratinocytes Keratinocytes make up the majority of cells in the epidermis, the outer layer of the skin. The progenitor cells that give rise to keratinocytes are found in the basal epidermal layer. As these…

The Metastatic Process in the Spread of Melanoma

Melanocytes and Keratinocytes

Melanoma: Causes and Prevention Melanoma is a type of skin cancer that arises from melanocytes, the pigmented cell type of the skin found in the outer layer of the skin (the epidermis). Although melanoma makes up only a…

3D Tissue Engineering for Studying Endometrial Dynamics

Female Reproductive Cells, Reproductive Cells

Structure and Remodeling of the Endometrium The uterus is lined by a specialized tissue called the endometrium, which is composed of a layer of epithelial cells and underlying stromal cells. During the course of a woman’s menstrual cycle,…

Mitochondrial Function Studied Using Decompression Sickness Conditions

Fibroblasts

Fibroblast Function in Connective Tissue Fibroblasts are the most common cell type found in connective tissue throughout the body. Their main role is to produce the extracellular matrix and collagen fibers that support the connective tissue structure. In…

Endothelial Cells Studied for Potential Therapeutic Targets in Acute Respiratory Distress Syndrome (ARDS)

Endothelial Cells

Endothelial Cells and Maintenance of Barrier Integrity Endothelial cells form the innermost layer of the blood vessels and mediate important interactions with the blood. The endothelial layer is a monolayer that acts as a barrier between the blood…

Renal and Bladder Cancer Research Utilizing Lifeline Products as Normal Controls

Bladder Epithelial Cells, Renal Epithelial Cells

Lifeline® Renal and Bladder Cells as Normal Tissue Controls Cancer treatments are designed to selectively target cancer cells, while sparing the normal cells of the body. To design drugs with these properties, researchers must understand what makes cancer…

Introducing NEW Induced Pluripotent Stem Cell – Derived Neural Stem Cells

Lifeline Cells and Media

Stem cells are specialized cell types characterized by two properties: self-renewal and the ability to give rise to, or differentiate into, multiple cell types. Totipotent stem cells are located only in developing embryos and have the capacity to…

Toxic Antiseptic Agents and Searching for New Treatments for Psoriasis

Melanocytes and Keratinocytes

Anatomy of the Skin, the Body’s Largest Organ The skin is the largest organ in the human body and is the largest area in contact with the external environment. In addition to providing physical protection, the skin also…

Senescence of Airway Epithelial Cells in Asthma

Lung/Airway Cells

Lung and Airway Cells: First-Line Barriers to the Outside World Breathing air is something we do without thinking. But while we go about our day, our respiratory systems are hard at work extracting oxygen from the air and…

Considering Differences Between Hormone Stages in Research of the Female Reproductive Tract

Female Reproductive Cells, Reproductive Cells

The Female Reproductive System Every month, the female reproductive system is responsible for the maturation and of an egg from one of the two ovaries. During this time, the inner lining of the uterus (or womb), called the…

Forward Motion Developing Liposomal Nanoparticle Delivery Systems

Endothelial Cells, Smooth Muscle Cells

Smooth Muscle Cells: Involuntary Contractile Cells Smooth muscle cells (SMCs) are spindle-shaped cells found throughout the body in the walls of many organs that have contractile function. For example, in the intestine, SMCs contract to push food and…

Quantifying the Effects of Hydrostatic Pressure and Homocysteine on Endothelial Cell Function

Endothelial Cells, Microvascular Endothelial Cells

Endothelial and Microvascular Endothelial Cells The cardiovascular system pumps blood to every tissue in our bodies through a network of arteries, veins, and capillaries. A key component of any blood vessel is a layer of endothelial cells, called…

Gingival Fibroblast Compatibility and Cytotoxicity of Dental Cement Compositions

Fibroblasts, Gingival Cells

Fibroblasts: The Main Components of Connective Tissue Fibroblasts are specialized cells that are often identified by their spindle-like shape and expression of the protein Vimentin. They are found in connective tissue throughout the body and where they produce…

Herpes Simplex Virus, Nerve Damage; Melanoma, Tumor Pathogenesis

Keratinocytes

Anatomy of the Skin The skin is composed of three layers: epidermis, dermis, and hypodermis. The epidermis is the outermost layer of the skin and is primarily composed of keratinocytes, the cells from which basal cell carcinoma develop.…

Mesenchymal Stem Cells: Osteoarthritis, Cell Therapy and Tissue Engineering

Mesenchymal Stem Cells

Mesenchymal Stem Cells and Chondrogenic Differentiation Mesenchymal stem cells (MSCs) are multipotent cells found in certain tissues, such as the bone marrow and fat. They have the capacity to differentiate into certain cell types, including osteoblasts (bone cells),…

Coronary Artery Smooth Muscle Cells: Mediators of Vascular Remodeling

Cardiac Cells, Smooth Muscle Cells

Smooth Muscle Cells and Phenotypic Switching Smooth muscle cells (SMCs) are contractile cells found in various organs including the prostate, bladder, and uterus. In particular, SMCs that are located in the blood vessels of the cardiovascular system are…

Cardiac and Endothelial Cells: Promoting Vasculature Homeostasis

Cardiac Cells, Endothelial Cells

Endothelial and Cardiac Cells The cardiovascular system is operated by the heart and blood vessels, or vasculature. The heart is a muscular organ that provides the force to pump the blood throughout the body in a network of…

Prostate Smooth Muscle Cells and Prostate Fibroblasts Added to Lifeline Catalog

Fibroblasts, Smooth Muscle Cells

Prostate Cancer and the Search for New Biomarkers The prostate is part of the male reproductive system, responsible for making and secreting part of the seminal fluid, which supports the health and survival of semen. The secretory cells…

New Diseased Cell Additions to Lung and Airway Catalog

Lung/Airway Cells

The Airway: More Than Just Oxygen Exchange When air is inhaled, it travels through the airway to the lungs, where the oxygen is exchanged for carbon dioxide. A single layer of epithelial cells lines the airway, providing a…