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Autophagy of Endothelial Cells Helping Maintain Homeostasis

Endothelial Cells

Large Vessel Endothelial Cells  Large vessel endothelial cells are found in arteries and veins and comprise the innermost layer of the vessel, forming a lining that separates the contents of the blood from the rest of the body.…

Arsenic Inhibition in Adipogenic Differentiation of Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal Stem Cells: Multipotent Progenitors of Bone, Fat, and Cartilage Mesenchymal stem cells (MSCs) are stem cells that can be found in the bone marrow, adipose tissue, and umbilical cord. These multipotent cells are capable of self-renewal, and…

Identifying New Biomarkers to Improve Diagnosis Using Prostate Epithelial Cells

Prostate Epithelial Cells

Prostate Cancer and Screening Prostate cancer is the second most common cancer type and second most common cause of cancer-related death in American men. Most prostate cancers are of epithelial origin, which means that the cells that become…

2018 Half-Year Review of Research with Lifeline® Products

Primary Cells

We’re halfway through 2018, which means it’s time for our bi-annual review. Every six months, we look back and review the research we have covered here on the blog, highlighting the different applications for which researchers have used…

Airway Epithelial Cells: Polarized Barrier Layer and the Latest Research

Lung/Airway Cells

Epithelial cells line many of the hollow organs in our bodies. A single layer of epithelium is composed of tightly packed individual epithelial cells that are connected to each other by protein complexes called tight junctions. Epithelia act…

Vascular Smooth Muscle Cells: Healing Wounds and Impacting Cardiovascular Health

Smooth Muscle Cells

Vascular Smooth Muscle Cells and Phenotype Switching Smooth muscle cells (SMCs) are specialized cell types found in the walls of many organs, including the stomach, small and large intestines, bladder, uterus, and blood vessels. In particular, the SMCs…

Keratinocytes and Dermal Fibroblasts: External Layers for Internal Protection

Melanocytes and Keratinocytes

The Multiple Layers and Cell Types of the Skin The skin is the ultimate barrier to the external environment, with a coverage area of the entire body. To perform its specialized functions, the skin is composed of multiple…

Endothelial Cells: Research in Cardiovascular Disease and Mesothelioma

Endothelial Cells

Endothelial Cells: Regulators of Vessel Homeostasis and Angiogenesis Endothelial cells line the blood vessels of the circulatory system and play major roles in cardiovascular homeostasis. Through extensive crosstalk with the circulating blood and various cell types contained in…

Determining the Role of JNK in Anoikis Using Mammary Epithelial Cells

Mammary Epithelial Cells

Mammary Gland Development The mammary gland is derived from the ectoderm, the outer layer of the embryo, and is formed into a series of ducts from which milk is produced. Although present at birth, the mammary gland undergoes…

Bladder Epithelial Cells: The Role of SETD6 on Bladder Cancer Growth and Survival

Bladder Epithelial Cells, Renal Epithelial Cells

The Excretory System: Waste Removal Experts Waste is removed from the body through an elegant filtration system that begins in the kidneys. The renal artery delivers blood to the kidneys, and in a series of filtration steps through…

Lifeline Cell Technology Adds Fallopian Tube Epithelial Cells to Catalog

Female Reproductive Cells

Now Available from Lifeline®: Fallopian Tube Epithelial Cells! The human female reproductive system is responsible for the development of eggs (the female gametes) the production of hormones (progesterone and estrogen), and importantly, supports development and delivery of a…

Airway Epithelium: Advances in Cell Culture Techniques Help Mimic this Complex Environment

Lung/Airway Cells

The Airway Epithelium and Air-Liquid Interface Culture A single later of epithelial cells lines many of our internal organs, including the airway. The airway epithelium is composed of multiple differentiated cell types that form a barrier against pathogens…

Smooth Muscle and Endothelial Cells: Their Critical Role in Blood Flow and Vascular Homeostasis

Smooth Muscle Cells

Large Vessel Endothelial and Smooth Muscle Cells The vessels that make up the circulatory system are multi-layered complex organs. Arteries carry oxygenated blood away from the heart to the tissues of the body and veins carry de-oxygenated blood…

Fibroblasts Studies: The Mitochondria and the Cytoskeleton, and Treating Yeast Biofilms

Fibroblasts

Fibroblasts are the main cell type in stromal tissue, the supporting tissue of an organ that contains structural and connective components. They are a multifunctional cell type whose main function is to secrete extracellular matrix, which forms the…

Microvascular Endothelial Cells and the Latest Circulatory System Research

Endothelial Cells

Endothelial Cells and the Circulatory System Vascular endothelial cells are multi-functional cells that line the vessels of the circulatory system. Endothelial cell monolayers form the innermost layer of vessels, serving protective and barrier functions, and interacting with factors…

Human Cells Research Studies Using Lifeline Cells: 2017 Review

Lifeline Cells and Media

Lifeline® Cells in 2017 It’s the end of the year again and here on the Lifeline® Cell Technology blog you have been keeping up with the various ways researchers from many fields have used Lifeline® cells. We are…

Keratinocytes and Melanocytes Skin Barrier Function Studies

Keratinocytes, Melanocytes and Keratinocytes

The Barrier Function of the Skin Protects the Body from the External Environment The skin is the largest organ of the body and as the outer covering of the body, has a significant protective role. The outermost layer…

Lifeline® Introduces New Cervical Epithelial Cells to Female Reproductive Catalog

Female Reproductive Cells

Cervical Cancer: Facts, Statistics, and Prevention The cervix is part of the female reproductive system and lies at the base of the uterus. The American Cancer Society estimates that in 2017, 12,820 women will be diagnosed with cervical…

Endothelial Cells: The Regulators of Blood Vessels

Endothelial Cells

Endothelial Cells and Culture Methods Endothelial cells line the blood and lymphatic vessels of the body, providing important regulation of vessel integrity, blood pressure, wound healing, and formation of new vessels. In particular, many endothelial cell functions are…

Multipotent and Differentiate Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal Stem Cells: Adult Stem Cells with Multiple Destinies Although totipotent stem cells exist only during early embryogenesis, many adult tissues retain adult stem cells, which are multipotent and can differentiate into multiple differentiated cell types. One of…