Endothelial cells line the blood vessels of the body and participate in significant crosstalk with the blood and tissues to maintain blood pressure and vessel homeostasis through regulation of vasodilation…
Cells of the Skin: Keratinocytes and Melanocytes The skin has three layers, the epidermis (outermost), the dermis (middle), and the hypodermis (the innermost). The epidermis is largely composed of keratinocytes,…
Fibroblasts: Important Players in Wound Healing Fibroblasts are a mesenchymal cell type, known for their spindle shape. Although they are present in most tissue types, they are often found in…
The excretory system starts at the kidneys, a pair of organs that detoxify and remove waste from the blood. This waste, in the form of urine, is transported through the…
The Eye: Window to the Brain The eyes are composed of many parts that together, sense and interpret light, enabling the formation of images via the brain. The front of…
Identifying the best cells to use as controls is critical. In particular, finding a “normal”, non-cancer control cell to test anti-cancer therapies is a challenge our customers often face. Lifeline®…
Smooth muscle cells (SMCs) are present in most contractile organs, including the bladder, gastrointestinal tract, and blood vessels. Smooth muscle cells in blood vessels are termed vascular smooth muscle cells…
For over 10 years, Lifeline Cell Technology has produced some of the world’s best normal human endothelial cells and normal human fibroblast cells. Additionally, we have developed low serum, serum-free,…
Endothelial cells form a monolayer that lines the lumen of blood vessels, provides an essential protective barrier, and regulates vessel and blood pressure homeostasis. Endothelial cells are also involved in…
The male gonads are the testes, which are housed in the scrotum. The testes produce sperm (male gametes) and testosterone (the main male hormone). Following production in the testes, sperm…
The epidermis is the outermost layer of the skin, which covers the entire body and provides an essential barrier against the external environment. The most common epidermal cell type is…
Like many organs, the airway is lined by a single layer of epithelial cells that form the barrier between the external and internal environments. The epithelium is the first line…
Fibroblasts are one of the most common types of stromal cells in the body and are responsible for generating extracellular matrix (ECM) components that support the tissue in which they…
It is the end of the year, so we thought we would take a look back to see how our cells have been used over the past year. Lifeline® provides…
The quality of cell culture media is critical for maintaining integrity of cells in culture and consistency between experiments. At Lifeline®, we have highly stringent quality control processes to ensure…
Smooth muscle cells are located in many organs throughout the body, most notably in the vasculature, but also in the bladder, uterus, and gastrointestinal system. They regulate contraction in…
The cardiovascular system is an extensive network that supports blood flow to the tissues of the body. Blood vessels have a specialized lining of endothelial cells that not only regulate…
Microvessels are the smallest blood vessels within the vasculature and include capillaries, arterioles, and venules. Microvessels play a significant role in cancer, as they can indicate neoangiogenesis, the growth of…
Mesenchymal stem cells (MSCs) are a component of the stroma in multiple tissues, including bone marrow, adipose tissue, the umbilical cord (or Wharton’s Jelly), and others. MSCs are multipotent adult…
Keratinocytes are the major cell type of the epidermis (the outermost skin layer) and are also found in the oral mucosa. They form the primary protective barrier between the internal…
