The Need for Better Preclinical Models Developing effective antiviral therapies for respiratory infections such as COVID-19, influenza, and RSV remains a persistent challenge—largely due to the limitations of current preclinical…
Asthma and Allergy Awareness Month May is Asthma and Allergy Awareness Month, an important time to recognize the challenges faced by individuals with asthma and allergies. Individuals suffering from asthma…
In keeping with the theme of last week’s blog on the development of a high throughput preclinical airway model for testing anti-viral therapeutics against influenza and coronaviruses, we will be…
A Pre-clinical Model to Evaluate Therapeutics for Respiratory Infections The current COVID-19 pandemic has highlighted the need for a robust pre-clinical model of the respiratory tract that can allow researchers…
Disease and Infection of the Respiratory Epithelium Oxygen is a necessity for all the cells in the human body to function. Our lungs and respiratory system bring air, containing oxygen…
The Respiratory Epithelium and Viral Infection There is no time like the present, while the world is fighting the virus that causes COVID-19 (SARS-CoV-2), to appreciate the deadly effects of…
Using Lifeline Cell Systems to Study Coronavirus Infection As the world is coping with the COVID-19 pandemic, researchers around the world are studying this novel virus to discover how it…
The Airway Epithelium and Damage from Smoking Every time we take a breath, the epithelial cells that line the airway and lungs are exposed to potential pollutants in the air.…
Small Airway Epithelial Cells The airway is lined by a layer of epithelial cells with multiple functions. In addition to providing a protective barrier function, the airway epithelium also secretes…
Lung and Airway Cells: First-Line Barriers to the Outside World Breathing air is something we do without thinking. But while we go about our day, our respiratory systems are hard…
The Airway: More Than Just Oxygen Exchange When air is inhaled, it travels through the airway to the lungs, where the oxygen is exchanged for carbon dioxide. A single layer…
Epithelial cells line many of the hollow organs in our bodies. A single layer of epithelium is composed of tightly packed individual epithelial cells that are connected to each other…
The Airway Epithelium and Air-Liquid Interface Culture A single later of epithelial cells lines many of our internal organs, including the airway. The airway epithelium is composed of multiple differentiated…
The Lung-Airway Epithelium When air enters the respiratory system, it travels through the trachea and into one of the two bronchi, which lead to either lung as they branch into…
Like many organs, the airway is lined by a single layer of epithelial cells that form the barrier between the external and internal environments. The epithelium is the first line…
The human airway (including the trachea and bronchi) is lined by a single layer epithelium that serves as the interface between the external and internal environments. It also provides a…
Where do Human Airway Cells Come From? Oxygenated air enters through the mouth or nose and passes into the trachea. The trachea branches into two bronchi, which lead to…
Research groups in the US recently studied two very different aspects of lung function, and they used Lifeline® airway cells to do it. Breathing is something we very much take…
