You searched for Microvascular endothelial cells

Circadian Clock Protein BMAL1 Protect Against UVB Damage

The skin is the largest organ of the human body composed of the epidermis (upper or outer layer) and the dermis (lower or inner layer). The epidermis, which is made up of three kinds of cells: keratinocytes, basal cells, and melanocytes, is susceptible to DNA damage caused by exposure to harmful solar ultraviolet radiation (UVR).…

August 5, 2021 by Lifeline® Cell Technology

Endothelial Cells

Endothelium Barrier Function Helps Mitigate Metastasis

Cancer Biology: Learnings from Transcriptomics Analysis Human Umbilical Vein Endothelial Cells, or HUVECs as they are more commonly known, are widely utilized as an in vitro model system for studying physiological and pathological processes of the vascular system. Endothelial cells line the inside of blood vessels and have a central role in angiogenesis, the formation…

June 10, 2021 by Lifeline® Cell Technology

Melanocytes and Keratinocytes

Mechanisms Driving Inflammation in Psoriasis

The Role of IL-22/PLCε Signaling in Psoriasis The outermost layer of the skin is the epidermis, which primarily functions as a protective mechanical barrier preventing the entry of harmful pathogens. The epidermis is predominantly composed of keratinocytes, but also contains other cell types like melanocytes, Langerhans cells, Merkel cells, and inflammatory cells. Psoriasis is a…

April 1, 2021 by Lifeline® Cell Technology

Blood Cells

The Role of Monocytes in Diabetic Retinopathy Pathogenesis

Peripheral blood cells are the circulating cellular components of blood consisting of red blood cells (erythrocytes), white blood cells (leukocytes), and platelets. White blood cells make up ~1% of all blood cells and each subpopulation has a specialized role in the immune system to safeguard against infection and injury. Monocytes, characterized by the expression of the CD14 cell surface receptor are bone marrow-derived…

March 19, 2021 by Lifeline® Cell Technology

Endothelial Cells

Extracellular Vesicles and Breast Cancer Metastasis

Endothelial Cells, Microvascular Endothelial Cells, and Cardiac Cells Cardiac cells and endothelial cells are two of the most important cell types that make up the heart tissue and blood vessels of the body’s vascular system. Almost all tissues rely on a blood supply for nutrients and gas exchange, which is supplied by a complex network…

February 19, 2021 by Lifeline® Cell Technology

Cell Culture Medium

Quality Media for Successful Cell Cultivation

The Cell Culture Media Makes the Culture Environment In order to successfully cultivate cells in the lab, researchers must use a suitable culture environment with the necessary nutrients for survival and proliferation, which is largely supplied by the cell culture medium. It also helps to regulate physiochemical parameters, such as pH, osmotic pressure and the…

February 4, 2021 by Lifeline® Cell Technology

Primary Cells

Research Highlights Featuring Lifeline’s Cell and Media

Semi-Annual Review of Lifeline Cell Systems in 2020 For those of you who follow the blog regularly, you know what time it is! Twice per year, we review some of the ways our cell systems can be used in different types of research. In addition to the three research topics below, we did some special…

June 26, 2020 by Lifeline® Cell Technology

Keratinocytes

Contributing Role of Infrared-A (IRA) Radiation in Photoaging

The Anatomy of the Skin and Aging The skin is the human body’s largest organ, responsible for providing a barrier to the external environment. The outermost layer of the skin is called the epidermis, which is continually exposed to a variety of stresses, including damage caused by the sun. The human epidermis has multiple layers,…

May 28, 2020 by Lifeline® Cell Technology

Lung/Airway Cells

Coronavirus, Influenza, and Respiratory Syncytial Virus Research

The Respiratory Epithelium and Viral Infection There is no time like the present, while the world is fighting the virus that causes COVID-19 (SARS-CoV-2), to appreciate the deadly effects of respiratory viruses. Respiratory viruses like influenza and coronaviruses infect the epithelium of the airway, which lines the inner surface of the trachea, bronchi, bronchioles, and…

May 13, 2020 by Lifeline® Cell Technology

Endothelial Cells

Potential Target Treatment of Vascular Dysfunction in Diabetes

The Circulatory System: The Blood Delivery System The circulatory system delivers the blood and oxygen that all tissues of the body require for normal operation. In particular, the arteries, veins, and capillaries that transport the blood throughout the body are lined by a layer of endothelial cells, which help to maintain blood and vessel homeostasis.…

February 20, 2020 by Lifeline® Cell Technology

Fibroblasts

Fibrotic Disease Research Using Human Dermal Fibroblasts

Fibroblasts and Wound Healing Fibroblasts are located in the connective tissue and produce the extracellular matrix, a supportive network that surrounds various cell types throughout the body. In addition to their role in tissue structure and support, fibroblasts also play a pivotal role in wound healing. The skin is a very dynamic organ that is…

December 12, 2019 by Lifeline® Cell Technology

Endothelial Cells

Prosthetic Vascular Graft Technology Improvement Research

Endothelial Cells and Peripheral Arterial Disease Endothelial cells comprise the innermost later of blood vessels, forming a barrier between the circulating blood and the tissues of the body. In particular, endothelial cells participate in extensive crosstalk with the blood to maintain vascular homeostasis. Endothelial cells are particularly important in cardiovascular diseases like atherosclerosis. Atherosclerosis occurs…

October 24, 2019 by Lifeline® Cell Technology

FBS Fetal Bovine Serum 35 mL

Fetal Bovine Serum 35 mL LifeFactor is for use with the appropriate basal medium and human fibroblasts, smooth muscle cells, endothelial cells, and microvascular endothelial cells.

September 23, 2019 by Lifeline® Cell Technology

Keratinocytes

Evaluating Chemotaxis of Epidermal Keratinocyte Migration

Keratinocytes: The Key Supporter of the Skin Barrier Keratinocytes are the most common cell type of the skin. They are present in the epidermis, which is the outermost layer of the skin, responsible for forming a barrier against the external environment and preventing water loss. The keratinocytes you see on your skin are mostly corneocytes,…

August 15, 2019 by Lifeline® Cell Technology

Melanocytes and Keratinocytes

Toxic Antiseptic Agents and Searching for New Treatments for Psoriasis

Anatomy of the Skin, the Body’s Largest Organ The skin is the largest organ in the human body and is the largest area in contact with the external environment. In addition to providing physical protection, the skin also regulates body temperature and provides sensory information. As a result, it must be resilient enough to survive…

March 15, 2019 by Lifeline® Cell Technology

Keratinocytes

Herpes Simplex Virus, Nerve Damage; Melanoma, Tumor Pathogenesis

Anatomy of the Skin The skin is composed of three layers: epidermis, dermis, and hypodermis. The epidermis is the outermost layer of the skin and is primarily composed of keratinocytes, the cells from which basal cell carcinoma develop. As keratinocytes mature, they become post-mitotic and lose their nucleus, becoming corneocytes, which are eventually shed from…

December 7, 2018 by Lifeline® Cell Technology

Lung/Airway Cells

New Diseased Cell Additions to Lung and Airway Catalog

The Airway: More Than Just Oxygen Exchange When air is inhaled, it travels through the airway to the lungs, where the oxygen is exchanged for carbon dioxide. A single layer of epithelial cells lines the airway, providing a layer of protection against airborne pathogens and toxins. The airway epithelium also produces mucus, which is an…

September 27, 2018 by Lifeline® Cell Technology

Melanocytes and Keratinocytes

Melanocytes, Dermal Fibroblasts, and Keratinocytes – Protectors to the External World

The Skin: A Multi-Cellular Barrier to the External World The skin is a multi-layered organ that covers the entire body and protects us from the external environment. The outermost layer, the epidermis, is largely composed of keratinocytes, which proliferate in the lower epidermis and migrate out, becoming post-mitotic and losing their nuclei, eventually becoming corneocytes.…

August 31, 2018 by Lifeline® Cell Technology

Melanocytes and Keratinocytes

Keratinocytes and Dermal Fibroblasts: External Layers for Internal Protection

The Multiple Layers and Cell Types of the Skin The skin is the ultimate barrier to the external environment, with a coverage area of the entire body. To perform its specialized functions, the skin is composed of multiple layers: the epidermis (outermost layer) and dermis (innermost layer). Below the dermis is the hypodermis, which is…

May 10, 2018 by Lifeline® Cell Technology

Lung/Airway Cells

Airway Epithelium: Advances in Cell Culture Techniques Help Mimic this Complex Environment

The Airway Epithelium and Air-Liquid Interface Culture A single later of epithelial cells lines many of our internal organs, including the airway. The airway epithelium is composed of multiple differentiated cell types that form a barrier against pathogens and irritants that are inhaled from the environment. Ciliated cells are so named for the hair-like projections…

February 16, 2018 by Lifeline® Cell Technology

Primary Cells, Stem Cells, and Optimized Media for Research

Search Results

Circadian Clock Protein BMAL1 Protect Against UVB Damage

Endothelium Barrier Function Helps Mitigate Metastasis

Mechanisms Driving Inflammation in Psoriasis

The Role of Monocytes in Diabetic Retinopathy Pathogenesis

Extracellular Vesicles and Breast Cancer Metastasis

Quality Media for Successful Cell Cultivation

Research Highlights Featuring Lifeline’s Cell and Media

Contributing Role of Infrared-A (IRA) Radiation in Photoaging

Coronavirus, Influenza, and Respiratory Syncytial Virus Research

Potential Target Treatment of Vascular Dysfunction in Diabetes

Fibrotic Disease Research Using Human Dermal Fibroblasts

Prosthetic Vascular Graft Technology Improvement Research

FBS Fetal Bovine Serum 35 mL

Evaluating Chemotaxis of Epidermal Keratinocyte Migration

Toxic Antiseptic Agents and Searching for New Treatments for Psoriasis

Herpes Simplex Virus, Nerve Damage; Melanoma, Tumor Pathogenesis

New Diseased Cell Additions to Lung and Airway Catalog

Melanocytes, Dermal Fibroblasts, and Keratinocytes – Protectors to the External World

Keratinocytes and Dermal Fibroblasts: External Layers for Internal Protection

Airway Epithelium: Advances in Cell Culture Techniques Help Mimic this Complex Environment

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