Human Epidermal Keratinocytes

Human Epidermal Keratinocytes, 10-Donor Pool

Lifeline® normal Human Primary Epidermal Keratinocytes (HEK), when grown in Lifeline® DermaLife K Keratinocytes Medium, provide an ideal serum-free culture model, for the study of wound healing, toxicology or epithelial biology. When in need of multiple keratinocyte cell lots, our Epidermal Keratinocyte 10-donor pool offers a wide range of donor demographics for research at an…
Human Epidermal Keratinocytes 10x

Epidermal Keratinocytes — Neonatal, Primary

Lifeline® Normal Human Epidermal Keratinocytes Neonatal (HEKn), when grown in Lifeline DermaLife K Keratinocytes Medium, provides an ideal serum-free culture model, for the study of wound healing, toxicology or epithelial biology. Your experimental outcomes will be true: Primary Keratinocytes are directly cultured from their source organ tissue and have not been modified in any way. This…
FC-0025, Adult Keratinocytes, 10x

Epidermal Keratinocytes — Adult, Primary

Lifeline® Normal Human Primary Epidermal Keratinocytes Adult (HEKa), when grown in Lifeline DermaLife K Keratinocyte Medium, provides an ideal serum-free culture model, for the study of wound healing, toxicology or epithelial biology. Primary Human Adult Keratinocytes are directly cultured from their source organ tissue and have not been modified in any way. This helps ensure…
Skin

The Role of Hedgehog Receptors in Regulating the Epidermal Immune Response

National Healthy Skin Month emphasizes the importance of maintaining healthy skin as a key aspect of overall health and well-being. The skin barrier, specifically the epidermis, protects the body against environmental threats, such as pathogens and chemicals, while also helping to maintain internal homeostasis and preventing water loss from the body. Improving our understanding of…
Face made out of bricks

Melanocytes, Dermal Fibroblasts, and Keratinocytes – Protectors to the External World

The Skin: A Multi-Cellular Barrier to the External World The skin is a multi-layered organ that covers the entire body and protects us from the external environment. The outermost layer, the epidermis, is largely composed of keratinocytes, which proliferate in the lower epidermis and migrate out, becoming post-mitotic and losing their nuclei, eventually becoming corneocytes.…
Woman with sunscreen on

Making Strides in Skin Cell Research Utilizing Lifeline® Keratinocytes and Melanocytes

Cells of the Skin: Keratinocytes and Melanocytes The skin has three layers, the epidermis (outermost), the dermis (middle), and the hypodermis (the innermost). The epidermis is largely composed of keratinocytes, which form a barrier against the external environment and play a role in wound repair. Melanocytes are another common cell type found in the skin.…
Skin cells on a woman's face

Epidermal Cells – Our First Line of Defense — and Recent Studies

The skin is a multi-layered organ that covers the entire body and serves as a barrier to the outside environment. The outermost layer is called the epidermis and is composed largely of keratinocytes, which function to provide a barrier to pathogens, temperature, UV radiation, and other damaging environmental factors. Also contained in the epidermis are…
Breast cancer screening

Novel Antibody-Drug Conjugate to Treat HER2-positive Metastatic Breast Cancer

Breast cancer is the most common cancer in women in the U.S., and HER2-positive breast cancer (HER2+ BC) accounts for 15-20% of all breast cancer diagnoses. HER2+ breast cancer is aggressive and fast-growing, historically associated with poor outcomes and higher mortality rates. The development of HER2-targeted therapies has significantly improved patient prognosis, with many experiencing good…