Diabetes, Insulin and Urinary Tract Infections
The Excretory System and Diabetes The excretory system consists of the kidneys and urinary tract, which together, filter and eliminate waste from the body. As blood circulates throughout the body,…
Prosthetic Vascular Graft Technology Improvement Research
Endothelial Cells and Peripheral Arterial Disease Endothelial cells comprise the innermost later of blood vessels, forming a barrier between the circulating blood and the tissues of the body. In particular,…
Investigating Biomarkers for Early Detection of Ovarian Cancer
The Female Reproductive System The female reproductive system produces the female gametes, or germ cells, called eggs. Once fertilized by a sperm cell, the male gamete, the resultant zygote develops…
Smooth Muscle Cells: Researching New Therapies for Bladder Disorders
Bladder Anatomy and Function The bladder is responsible for collecting and storing the urine produced by the kidneys until it is voided from the body during urination. The inner epithelial…
Prostate Cancer and Development of Biomarkers
The prostate is a walnut-shaped male organ responsible for secreting prostatic fluid, which is an important component of seminal fluid. This year, the American Cancer Society estimates that 31,620 men…
Research Using Lifeline® MSCs to Develop Therapies for Bone Defects
Multipotent, Pluripotent, and Totipotent Stem Cells and Induced Pluripotent Stem Cells Stem cells are undifferentiated cells that have two characteristics: they give rise to different mature cell types and have…
Evaluating Chemotaxis of Epidermal Keratinocyte Migration
Keratinocytes: The Key Supporter of the Skin Barrier Keratinocytes are the most common cell type of the skin. They are present in the epidermis, which is the outermost layer of…
Searching for Optimal Models for Endothelial Cell 3D Culture
Endothelial Cells and the Extracellular Matrix (ECM) Endothelial cells line the vessels of the circulatory system and provide important support for vessel homeostasis, wound repair, and the inflammatory response. The…
Lifeline®Research Products in Action: Half-Year Review 2019
Lifeline® Products in Research Studies in First Half of 2019 It’s that time again! Time for our mid-year review, where we look back on the last six months and review…
Airway Epithelial Cells and Smoke Exposure in COPD Research
Small Airway Epithelial Cells The airway is lined by a layer of epithelial cells with multiple functions. In addition to providing a protective barrier function, the airway epithelium also secretes…
Keratinocytes in Research: Epidermal Differentiation and Senescence
Function and Differentiation of Keratinocytes Keratinocytes make up the majority of cells in the epidermis, the outer layer of the skin. The progenitor cells that give rise to keratinocytes are…
The Metastatic Process in the Spread of Melanoma
Melanoma: Causes and Prevention Melanoma is a type of skin cancer that arises from melanocytes, the pigmented cell type of the skin found in the outer layer of the skin…
3D Tissue Engineering for Studying Endometrial Dynamics
Structure and Remodeling of the Endometrium The uterus is lined by a specialized tissue called the endometrium, which is composed of a layer of epithelial cells and underlying stromal cells.…
Mitochondrial Function Studied Using Decompression Sickness Conditions
Fibroblast Function in Connective Tissue Fibroblasts are the most common cell type found in connective tissue throughout the body. Their main role is to produce the extracellular matrix and collagen…
Endothelial Cells Studied for Potential Therapeutic Targets in Acute Respiratory Distress Syndrome (ARDS)
Endothelial Cells and Maintenance of Barrier Integrity Endothelial cells form the innermost layer of the blood vessels and mediate important interactions with the blood. The endothelial layer is a monolayer…
Renal and Bladder Cancer Research Utilizing Lifeline Products as Normal Controls
Lifeline® Renal and Bladder Cells as Normal Tissue Controls Cancer treatments are designed to selectively target cancer cells, while sparing the normal cells of the body. To design drugs with…
Introducing NEW Induced Pluripotent Stem Cell-Derived Neural Stem Cells
Stem cells are specialized cell types characterized by two properties: self-renewal and the ability to give rise to, or differentiate into, multiple cell types. Totipotent stem cells are located only…
Toxic Antiseptic Agents and Searching for New Treatments for Psoriasis
Anatomy of the Skin, the Body’s Largest Organ The skin is the largest organ in the human body and is the largest area in contact with the external environment. In…
Senescence of Airway Epithelial Cells in Asthma
Lung and Airway Cells: First-Line Barriers to the Outside World Breathing air is something we do without thinking. But while we go about our day, our respiratory systems are hard…
Considering Differences Between Hormone Stages in Research of the Female Reproductive Tract
The Female Reproductive System Every month, the female reproductive system is responsible for the maturation and of an egg from one of the two ovaries. During this time, the inner…