Endothelial Cells: Master Regulators of Vascular Function
Endothelial cells line blood vessels and are crucial for maintaining proper vessel homeostasis and blood flow. They are essential for regulating thrombosis (blood clotting), vessel growth, and angiogenesis (formation of…
Gingival Structure, Function, and the Latest Research
The gingiva (or gums) is the tissue that surrounds and protects the teeth and underlying bone. The gingiva is attached to the tooth, forming a seal that protects the underlying…
Dermal Fibroblasts Used to Study Induced Pluripotent Stem Cells and UV Radiation
The skin is the body’s first level of defense against the external environment. It is composed of multiple tissue layers that are held together by connective tissue, which supports and…
Mesenchymal Stem Cells Latest Research Studies
Mesenchymal stem cells (MSCs) are stromal cells that are primarily found in the bone marrow, but can be isolated from other locations, including adipose, the umbilical cord as well as…
Vascular Smooth Muscle Cells and the Latest Research Studies
Vascular smooth muscle cells (VSMCs) line blood vessels, providing a structural foundation and controlling vessel constriction and relaxation, which regulates blood flow and pressure. Vascular smooth muscle cell contraction is…
Epidermal Cells – Our First Line of Defense — and Recent Studies
The skin is a multi-layered organ that covers the entire body and serves as a barrier to the outside environment. The outermost layer is called the epidermis and is composed…
Studies Using Lifeline® Human Primary Cells for Transfection
Lifeline® offers a large number of primary cells for your research needs, many of which can be efficiently transfected. Importantly, Lifeline® cells can be used as normal control cells for…
The Respiratory System and the latest Human Airway Cells Research
Where do Human Airway Cells Come From? Oxygenated air enters through the mouth or nose and passes into the trachea. The trachea branches into two bronchi, which lead to…
The Kidneys, the Renal System, and the Latest Research
The kidneys are an important component of the renal system. Blood is carried to the kidneys where waste products are filtered in structures called nephrons. Each nephron is composed of…
Human Endothelial Cells Use in Research
The Circulation System and Endothelial Cell Function A healthy circulation system is critical for normal physiological function; Arteries, veins, and, capillaries transverse the body providing an essential blood supply to…
Human Female Reproductive Cells
Human Female Reproductive System The female reproductive system that supports the fertilization and growth of an embryo includes the vagina, ovaries, fallopian tubes and the uterus. These organs all have…
Human Male Reproductive Cells — Recent Studies and Background
Human Male Reproductive System The male reproductive system includes external organs such as the penis and scrotum and internal organs such as the epididymis, vas deferens, and accessory glands (seminal…
Keratinocytes: Guardians of the Skin!
Your skin is your strongest form of protection from a plethora of environmental insults. From bad weather, to pathogens, to UV exposure, to injury, skin is the barrier that not…
Fibroblasts: Oh, the Places You Will Go . . .
What are Fibroblasts? Fibroblasts are connective tissue cells that secrete the components that make up the extracellular matrix and the stroma. Both these structures provide a supportiv framework that keeps cells, tissues,…
Smooth Muscle Cells — The Involuntary Muscle Cells
Smooth muscle cells (SMCs) are involuntary, non-striated muscle cells that line the insides of hollow organs such as arteries, lungs, bladder, the digestive system, and the reproductive system. SMC function…
Targeting Epithelial Cells in Bladder Cancer
(This is a summary of the state of bladder cancer in the US, along with summaries of two recent bladder cancer research studies using Lifeline® Normal Human Bladder Epithelial Cells.)…
Optimal Model Systems for Breast Cancer Research
According to the National Breast Cancer Foundation, 1 in 8 women will get breast cancer in their lifetime. This translates to approximately 220,000 diagnoses and more than 40,000 deaths per…
All About Human Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) originate from the mesoderm during embryonic development and give rise to multiple different tissue types including bone, cartilage, and fat. It is important to note that…
Endothelial Cells: the Good, the Bad, and the Source
The Good: Endothelial cells make up the inner lining of blood and lymphatic vessels. Vascular endothelial cells specifically line the entire circulatory system including small blood vessels (microvascular), large blood vessels…