endothelial cells as regulators of blood vessel homeostatis
Endothelial Cells

Endothelial Cells: Regulators of Blood Vessel Homeostasis

Endothelial cells line the blood vessels of the body and participate in significant crosstalk with the blood and tissues to maintain blood pressure and vessel homeostasis through regulation of vasodilation and vasoconstriction. In particular, endothelial cells have been implicated in atherosclerosis, a significant health issue and risk factor for heart attackand stroke. Atherosclerosis is characterized…
June 25, 2017 by Lifeline® Cell Technology
Human Endothelial Cells as Barriers
Endothelial Cells

Endothelial Cells as Blood Vessel Barriers — The Latest Research Studies

Endothelial cells form a monolayer that lines the lumen of blood vessels, provides an essential protective barrier, and regulates vessel and blood pressure homeostasis. Endothelial cells are also involved in forming new blood vessels, a process called angiogenesis. During cancer cell metastasis, cancer cells break off from a primary tumor and travel through the bloodstream…
March 5, 2017 by Lifeline® Cell Technology
cardiovascular system diagram
Endothelial Cells

Endothelial Cells: Cardiovascular Multi-Taskers in the Latest Studies

The cardiovascular system is an extensive network that supports blood flow to the tissues of the body. Blood vessels have a specialized lining of endothelial cells that not only regulate vessel homeostasis, but also form a protective barrier between factors in the blood and the internal environment. They have substantial migratory ability and also participate…
November 11, 2016 by Lifeline® Cell Technology
Skin cells on a woman's face
Melanocytes and Keratinocytes

Epidermal Cells – Our First Line of Defense — and Recent Studies

The skin is a multi-layered organ that covers the entire body and serves as a barrier to the outside environment. The outermost layer is called the epidermis and is composed largely of keratinocytes, which function to provide a barrier to pathogens, temperature, UV radiation, and other damaging environmental factors. Also contained in the epidermis are…
November 16, 2015 by Lifeline® Cell Technology
VascuLife EnGS-Mv Microvascular Endothelial Medium Complete Kit LL-0004

VascuLife® EnGS-Mv Microvascular Endothelial Kit

VascuLife® EnGS-Mv Medium (containing Endothelial Cell Growth Supplement) is optimized for the culture of Human Primary Microvascular Endothelial Cells. VascuLife culture medium supports the rapid proliferation of these Primary Microvascular Endothelial Cells in a 5% serum environment. Primary Microvascular Cells cultured in VascuLife medium out-perform Primary Cells grown in any similar medium.  You’ll get consistently…
September 1, 2015 by Lifeline® Cell Technology

VascuLife® VEGF-Mv Endothelial Complete Kit

VascuLife® VEGF-Mv (containing Vascular Endothelial Growth Factor) is a medium optimized for the culture of Primary Human Microvascular Endothelial Cells. VascuLife supports the rapid proliferation of these cells in a 5% serum environment. Primary Microvascular Endothelial Cells cultured in VascuLife Microvascular medium medium out-perform Primary Cells grown in any similar medium.  You’ll get consistently reproducible…
September 1, 2015 by Lifeline® Cell Technology
Pulmonary Artery Endothelial Cells 10x FC-0055
Endothelial Cells

Endothelial Cells: the Good, the Bad, and the Source

The Good: Endothelial cells make up the inner lining of blood and lymphatic vessels. Vascular endothelial cells specifically line the entire circulatory system including small blood vessels (microvascular), large blood vessels (macrovascular), and the heart. Here is a short list of their important functions in the human body: Control blood pressure by modulating vascular tone Prevent…
April 20, 2015 by Lifeline® Cell Technology
Man smoking outside
Cardiac Cells

Strategies for Cardiovascular Risk Reduction in Smokers

For American Heart Month, we want to highlight the importance of advancing cardiovascular research to better understand vascular health, heart function, disease mechanisms, and to develop new therapies for disease treatment. Cardiovascular disease (CVD) remains the leading cause of death in the United States, claiming the lives of approximately 695,000 Americans in 2021 alone. Cigarette…
February 21, 2024 by Lifeline® Cell Technology
stethoscope heart blog
Endothelial Cells

Impact of E-Cigarette Smoke on Cardiovascular Function

Cigarette smoking is one of the primary risk factors for cardiovascular disease (CVD). In fact, the American Heart Association reports that smoking-related diseases are responsible for > 440,000 deaths in the US each year. Cigarette smoke contains hundreds of chemical toxicants, which can damage the cardiovascular system, and increase the risk of developing atherosclerosis. Atherosclerosis…
November 4, 2021 by Lifeline® Cell Technology
skin irritation
Melanocytes and Keratinocytes

Mechanisms Driving Inflammation in Psoriasis

The Role of IL-22/PLCε Signaling in Psoriasis The outermost layer of the skin is the epidermis, which primarily functions as a protective mechanical barrier preventing the entry of harmful pathogens. The epidermis is predominantly composed of keratinocytes, but also contains other cell types like melanocytes, Langerhans cells, Merkel cells, and inflammatory cells. Psoriasis is a…
April 1, 2021 by Lifeline® Cell Technology
retinopathy
Blood Cells

The Role of Monocytes in Diabetic Retinopathy Pathogenesis

Peripheral blood cells are the circulating cellular components of blood consisting of red blood cells (erythrocytes), white blood cells (leukocytes), and platelets. White blood cells make up ~1% of all blood cells and each subpopulation has a specialized role in the immune system to safeguard against infection and injury. Monocytes, characterized by the expression of the CD14 cell surface receptor are bone marrow-derived…
March 19, 2021 by Lifeline® Cell Technology