Dermal Fibroblasts and Cancer
Lifeline Cells and Media

Research Applications of Lifeline Cells and Culture Media

Many research groups have demonstrated the diversity of our many cell types. A few of the many research applications are highlighted here: Lifeline® Dermal Fibroblasts as normal, non-transformed control cells Prostate and pancreatic cancer are two of the most deadly human cancers with limited treatment options. Therefore, there is much interest in developing new targeted…
March 27, 2016 by Lifeline® Cell Technology

FibroLife S2 Fibroblast Medium Complete Kit

Optimized for Culturing Primary Human Fibroblasts and Pre-Adipocyte Mesenchymal Stem Cells in a Low-Serum Environment.  FibroLife S2 supports the growth of these cells in a 2% serum environment at rates equal to or greater than comparable media supplemented with 2% to 10% FBS. Primary Cells cultured in FibroLife medium out-perform cells grown in any similar medium…
September 9, 2015 by Lifeline® Cell Technology

FibroLife Fibroblast Serum Free Medium Complete Kit

FibroLife Serum-Free is a defined medium optimized specifically for the serum-free culture of Primary Human Fibroblasts.  FibroLife Serum-Free supports the growth of these Primary Cells in a serum-free environment at rates equal to or greater than media supplemented with 2% to 10% FBS. Primary Fibroblasts cultured in Lifeline® medium out-perform cells grown in any similar medium. …
September 1, 2015 by Lifeline® Cell Technology
Doctor treating patient
Gingival Cells

A Long-Term Bioreactor-based In Vitro Oral Cavity Model to Study Host-Microbiome Interactions

Oral Cancer Awareness Month The oral cavity is home to a diverse community of microorganisms—bacteria, fungi, and viruses—collectively known as the oral microbiome. When host-microbiome interactions function properly, they support both oral and overall health; however, imbalances can contribute to conditions like periodontitis (gum disease) and may even increase the risk of oral cancer. Oral…
April 15, 2025 by Lifeline® Cell Technology
Atherosclerosis
Cardiac Cells

Breast Cancer Drug Neratinib Found to Protect Against Atherosclerosis

American Heart Month Atherosclerosis is a common disease that develops when the buildup of fats, cholesterol and other substances in and on the artery walls. This buildup—called plaque—can cause arteries to narrow, blocking blood flow or even burst, resulting in a blood clot. Heart diseases linked to atherosclerosis, or atherosclerotic cardiovascular disease (ASCVD), remains the…
February 13, 2025 by Lifeline® Cell Technology
Man smoking outside
Cardiac Cells

Strategies for Cardiovascular Risk Reduction in Smokers

For American Heart Month, we want to highlight the importance of advancing cardiovascular research to better understand vascular health, heart function, disease mechanisms, and to develop new therapies for disease treatment. Cardiovascular disease (CVD) remains the leading cause of death in the United States, claiming the lives of approximately 695,000 Americans in 2021 alone. Cigarette…
February 21, 2024 by Lifeline® Cell Technology
stethoscope heart blog
Endothelial Cells

Impact of E-Cigarette Smoke on Cardiovascular Function

Cigarette smoking is one of the primary risk factors for cardiovascular disease (CVD). In fact, the American Heart Association reports that smoking-related diseases are responsible for > 440,000 deaths in the US each year. Cigarette smoke contains hundreds of chemical toxicants, which can damage the cardiovascular system, and increase the risk of developing atherosclerosis. Atherosclerosis…
November 4, 2021 by Lifeline® Cell Technology
inflammation of the mouth
Fibroblasts, Gingival Cells

Gingival Fibroblast Compatibility and Cytotoxicity of Dental Cement Compositions

Fibroblasts: The Main Components of Connective Tissue Fibroblasts are specialized cells that are often identified by their spindle-like shape and expression of the protein Vimentin. They are found in connective tissue throughout the body and where they produce collagen and the extracellular matrix. Fibroblasts are also key players in inflammation and wound healing, and their…
January 5, 2019 by Lifeline® Cell Technology